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董婷 教授

基本信息:

名: 董婷

出生日期: 19891223

聯系方式: tingdong2021@sdu.edu.cn18854152103

工作單位: 推荐几个网赌网站

通訊地址: 濟南市文化西路44号推荐几个网赌网站天然藥物化學研究所

個人簡介

董婷,生物化學與分子生物學博士,推荐几个网赌网站教授,齊魯青年學者,博士生導師。主要從事天然産物重編程巨噬細胞用于免疫代謝疾病的機制研究。迄今為止申請人累計發表學術論文14篇,含第一/共同第一/通訊作者論文11篇,其中影響因子10分以上期刊論文7篇(2Nature Communications1Journal of the American Chemical Society2Angewandte Chemie International Edition1Pharmacology & Therapeutics1Journal of Advanced Research),參與申請國際專利2項,獲得麻省理工學院博士後資助項目一項(MIT postdoctoral fellowship)。博士後期間在哈佛大學諾獎得主E. J. Corey教授實驗室做短期化學生物學顧問。目前是國際學術期刊《Natural Products and Bioprospecting》、《Annals of Community Medicine and Primary Health Care》、IUBMB Life的編委,并擔任多個SCI期刊的審稿人,包括PeerJ, Heliyon, Biomedicine & Phamacotherapy, Bone Research以及Internaltionl Journal of Oral Science

教育背景:

2011-09 2016-06,  北京協和醫學院, 生物化學與分子生物學 , 博士

2007-09 2011-06,  西北農林科技大學, 應用化學, 學士

研究經曆:

2021 至今,  山東大學, 藥學院, 教授

2017 2021,  麻省理工學院,博士後

2016 2017,  哈佛醫學院,哈佛大學幹細胞與組織再生生物學系以及丹娜法伯癌症研究所,博士後

研究方向:

1. mRNA體内可視化工具的開發以及應用

2.免疫重編程抗衰老機制研究

承擔課題:

1. 山東省海外優青,天然藥物化學(No. 2022HWYQ-033),60萬,2022.04-2025.03(在研)

2. 國家自然科學基金-青年項目,GPR3/β-arrestin2信号軸代謝重編程巨噬細胞的機制研究(No. 82204404,30萬,2023.01-2025.12(在研)

代表性文章

Huirui Wang, Yinghui Gao, Li Wang, Yang Yu, Jiaozhen Zhang, Chunyu Liu, Yaxin Song, Haochuan Xu, Jingcheng Wang, Hongxiang Lou*, Ting Dong*(通訊). Lung specific homing of diphenyleneiodonium chloride improves pulmonary fibrosis by inhibiting macrophage M2 metabolic program. Journal of Advanced Research. 2022. https://doi.org/10.1016/j.jare.2022.04.012

Ting Dong#, Xinyi Chen#, Haochuan Xu, Yaxin Song, Huirui Wang, Yinghui Gao, Jingcheng Wang, Ruiqing Du, Hongxiang Lou*, Ting Dong*(通訊). Mitochondrial metabolism mediated macrophage polarization in chronic lung diseases. Pharmacology & Therapeutics, 2022 Nov; 239: 108208.

Yingzhong Li#, Nikola A Ivica#, Ting Dong#(共一), Dimitrios P Papageorgiou, Yanpu He, Douglas R Brown, Marianna Kleyman, Guangan Hu, Walter W Chen, Lucas B Sullivan, Amanda Del Rosario, Paula T Hammond, Matthew G Vander Heiden, Jianzhu Chen. MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Nature. Communications, 2020, 11, 4837.

Guangan Hu*, Ting Dong, Sisi Wang, Hongyu Jing, and Jianzhu Chen*. Vitamin D3-Vitamin D receptor axis suppresses pulmonary emphysema by maintaining alveolar macrophage homeostasis and function. EBioMedicine, 2019, 45, 563-577.

Xiaohui Liu#, Ting Dong#(共一), Yu Zhou, Niu Huang and Xiaoguang Lei*. Exploring the Binding Proteins of Glycolipids with Bifunctional Chemical Probes. Angewandte Chemie International Edition, 2016, 55, 14330.

Ting Dong#(共一), Chao Li#, Xing Wang, Longyang Dian, Xiuguo Zhang, Lin Li, She Chen, Ran Cao, Li Li, Niu Huang, Sudan He* & Xiaoguang Lei*. Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine. Nature Communications, 2015, 6, 6522.

Ting Dong, Weilong Liu, Zhirong Shen, Lin Li, She Chen & Xiaoguang Lei*. Pterisolic Acid B is a Nrf2 Activator by Targeting C171 within Keap1-BTB Domain. Scientific Reports, 2016, 6, 19231.

Ting Dong, Liao Daohong, Liu Xiaohui & Xiaoguang Lei*. Using Small Molecules to Dissect Non-apoptotic Programmed Cell Death: Necroptosis, Ferroptosis, and Pyroptosis. ChemBioChem 2015, 16, 2557.

Zhang Xiaoyun#, Dong Ting#(), Li Qiang, Xiaohui Liu, Xiaoying Yang & Xiaoguang Lei*. Second Generation TQ-Ligation for Cell Organelle Imaging. ACS Chemical Biology, 2015, 10, 1676.

Chao Li#, Ting Dong#(), Qiang Li & Xiaoguang Lei*. Probing the Anti-cancer Mechanism of (-)-Ainsliatrimer A through Diverted Total Synthesis and Bioorthogonal Ligation. Angewandte Chemie International Edition, 2014. 53, 12111.

Qiang Li#, Ting Dong#(), Xiaohui Liu & Xiaoguang Lei*. A Bioorthogonal Ligation Enabled by Click Cycloaddition of o‑Quinolinone Quinone Methide and Vinyl Thioether. Journal of the American Chemical Society, 2013, 135, 4996. (News story describing this work was highlighted in Chem. & Eng. News. 2013, 14, 37.)

Qiang Li, Ting Dong, Xiaohui Liu, Xiaoyun Zhang & Xiaoguang Lei*. ortho-Quinolinone Quinone Methide Finds its Applications in the Bioorthogonal Ligation. Current Organic Chemistry, 2014, 18, 86.

Chao Li, Ting Dong, Longyang Dian, Weidong Zhang & Xiaoguang Lei*. Biomimetic syntheses and structural elucidation of the apoptosis-inducing sesquiterpenoid trimers:(-)ainsliatrimers A and B. Chemical Science, 2013, 4, 1163.

專利

Xiaoguang Lei, Chao Li, Ting Dong. Sesquiterpenoids, US patent, 20170044180, 02-06-2017.

Chen Jianzhu,Nikola,Li Yingzhong,Dong Ting. TARGET FOR MODULAT ING BODY MASS, US patent, WO 2022/051254 A210-03-2021.

會議報告

特邀報告《2ND International Conference on Microbiology & Infectious Diseases(2022)

麻省理工學術年會 (2019)

麻省理工學術年會 (2018)